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 CENTRE FOR DNA NANOTECHNOLOGY

Welcome

Center for DNA Nanotechnology (CDNA) was founded in 2007 as a center of excellence funded by the Danish National Research Foundation (Danmarks Grundforskningsfond).

The center is based at the Interdisciplinary Nanoscience Center (iNANO) at Aarhus University, Denmark, with three American collaborators at North Carolina State University - Raleigh, Arizona State University and Harvard University. The purpose of the center is to conduct basic research within the field of DNA Nanotechnology and we have gathered an interdisciplinary team of around 35 researchers and students from chemistry, physics and molecular biology.

We exploit the self-assembling capability of oligonucleotides to study and control the assembly of materials at the nanoscale. This research ranges from assembly of nucleotide derivatives on surfaces, DNA-directed chemistry and DNA-based sensors to formation of complex DNA nanostructures and the interactions of such structures with biological systems. Among the key competences present at the center for the formation and characterization of such structures are synthetic organic chemistry, molecular biology, and scanning probe microscopy.

Examples on the research contributions from CDNA are self-assembly of a DNA-origami box with a controllable lid (Nature 2009), single-molecule chemical reactions on DNA origami (Nature Nanotechnology 2010), DNA-templated protein conjugation including antibodies (Nature Chemistry 2014) and self-assembly nanostructures from in vitro transcriped RNA (Science 2014).

Thank you for visiting our homepage and if you have further questions please don’t hesitate to contact us.

Kurt Gothelf, Director of CDNA, kvg@chem.au.dk

CDNA meetings - fall 2014

The preliminary dates for CDNA meetings this fall are the following:


Date Time Place Speakers
Dec 11 15:15 Aud G1 (Department of Mathematics, 1532-116)

Jie Song 

Anne Louise Bank Kodal

Nov 13 15:15 Aud G1 (Department of Mathematics, 1532-116) 

Detector Gadget, BIOMOD team 2014

Denis Selnihhin, PhD student in Ebbe’s group

  • Titel: DNA origami biosensor.

Vipin Kumar, Post doc in Kurt’s group

  • Title: Acyclic (L)-Threonine Nucleic Acid and Saporin-Oligonucleotide conjugates for controlling the toxicity of Ribosome-inactivating protein (RIP).
*Oct 20 09:00-11:45 The iNANO Auditorium (1593-012) Kurt Gothelf, Ebbe S. Andersen, Ilenia Manuguerra, Rui Campos, Søren Preus
Sep 23 15:15 Aud. VI (Chemistry) Mikael Madsen, Mette Bruun Jepsen

* Meeting with the Danish National Research Foundation.

Latest News 041114

Dec 2014 Kurt Gothelf receives DKK 24.3m from the Innovation Foundation for improving measurement of medication levels in patients.
Dec 2014 PhD defence: Christian Bortolini is defending his PhD thesis, "Self-assembly of amyloid-like fibrils at nanoscale", on December 1, 2014, at 13:15 in Aud D1 (1531-113, Department of Mathematics).
Nov 2014 Prof. Thomas Carell, Ludwig-Maximilians-Universität Munich, visits iNANO on November 27 2014 at 15:15 and will give at talk on DNA methylation in Aud I at Department of Chemisty (1514-213). Tentative title: "The Chemistry of Genome Maintenance".
Nov 2014 PhD defence: Christian Bech Rosen is defending his PhD thesis, "Synthetic Approaches for the Assembly and Study of Biomolecules", on November 27 2014 at 10:15 in Lakeside Lecture Theatres (Eduard Biermann auditorium,1252-204).
Nov 2014

Congratulations to Detector Gadget, our team of students from Centre for DNA Nanotechnology! Detector Gadget was placed 3rd in “Best Wiki” and “Best YouTube video” at the International Bio-molecular Design Competition (BIOMOD) 2014. Detector Gadget also ended up in the top category, “GOLD”, of Project Awards. Go check out the wiki and YouTube video made by Detector Gadget. Read the AU ST news here and the press release in Jyllands Posten here (danish).

Oct 2014 PhD defence: Jesper Vinther Sørensen is defending his PhD thesis, "”Engineering the Bottom-Room for Organic Electronics Using DNA Nanotechnology and Electrografting”" on October 28 2014 at 12:15 in Aud I at Department of Chemistry (1514-213)
Oct 2014 Senior lecturer Jussi Toppari, University of Jyvälskä, visits iNANO on October 28 2014 at 10:15 in iNANO aud (1593-012) and will give a talk on "Possible conductivity of self-assembled DNA structures?".
Oct 2014 PhD defence: Dennis Jul Hansen is defending his PhD thesis, "Synthesis of nucleoside analogues to introduce new functionalities of nucleic acids" on October 23 2014 at 10:15 in Aud I at Department of Chemistry (1514-213)
Oct 2014 Professor Sijbren Otto, University of Groningen, visits iNANO on October 22 2014 at 15:15 in iNANO aud. (1593-012) and will give a talk on "Systems Chemistry: Molecular Recognition, Catalysis and Self-Replication".
Oct 2014 Dr. Matteo Castronovo, Department of Biology, Temple University, USA, visits iNANO on October 23 2014 at 13:15 in iNANO aud (1593-012) and will give a talk on "Nucleic Acid Density is a Crucial Determinant of Enzyme Diffusion, Recognition, and Reactivity at the Nanoscale".
Oct 2014 Professor Chunhai Fan, Shanghai Institute of Applied Physics (SINAP), visits iNANO on October 3 2014 at 10:15 in iNANO aud. (1593-012) and will give a talk on "Creating dynamic organization with DNA nanotechnology".
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Revised 2014.12.16

Aarhus University
Nordre Ringgade 1
DK-8000 Aarhus C

Email: au@au.dk
Tel: +45 8715 0000
Fax: +45 8715 0201

CVR no: 31119103

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