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Centre for DNA Nanotechnology (CDNA) is a centre of excellence funded by the Danish National Research Foundation (Danmarks Grundforskningsfond).

The center is based at the Interdisciplinary Nanoscience Center (iNANO) at Aarhus University, Denmark, in close collaboration with two research groups at Duke University, USA and Arizona State University, USA.  The purpose of the centre is to conduct basic research within the field of DNA Nanotechnology and we have gathered an interdisciplinary team of around 35 researchers and students from chemistry, physics and molecular biology.

We exploit the self-assembling capability of oligonucleotides to study and control the assembly of materials at the nanoscale.  This research ranges from assembly of nucleotide derivatives on surfaces, DNA-directed chemistry and DNA-based sensors to formation of complex DNA nanostructures and the interactions of such structures with biological systems. Among the key competences present at the center for the formation and characterization of such structures are synthetic organic chemistry, molecular biology, and scanning probe microscopy.

Examples on the contributions from CDNA since its establishment in 2007 are:  self-assembly of DNA bases on surfaces studied by STM (Science 2008), development of the first RNA aptamer-based electrochemical sensor (J. Am. Chem. Soc. 2008), synthesis and assembly of or molecular rods along the axis of DNA (Angew. Chem. 2008), development of a software package for design of DNA Origami (ACS Nano 2008, the software is freely available at this home page), the folding of a viral DNA sequence into a box with a controllable lid (Nature 2009), and recently we reported on single-molecule chemical reactions on DNA origami (Nature Nanotechnology 2010).

Thank you for visiting our homepage and if you have further questions please don’t hesitate to contact us.

Kurt Gothelf
Director of CDNA

Latest News 150914

Oct 2014 PhD defence: Jesper Vinther Sørensen is defending his PhD thesis, "”Engineering the Room at the Bottom for Organic Electronics Using Triazenes for Electrografting & DNA-Nanotechnology Combined with Top-Down Nanolithography”" on October 28 2014 at 12:15 in Aud I at Department of Chemistry (1514-213)
Oct 2014 Senior lecturer Jussi Toppari, University of Jyvälskä, visits iNANO on October 28 2014 at 10:15 in Aud I (Department of Chemistry - 1514-213) and will give a talk on "Possible conductivity of self-assembled DNA structures?".
Oct 2014 PhD defence: Dennis Jul Hansen is defending his PhD thesis, "Synthesis of nucleoside analogues to introduce new functionalities of nucleic acids" on October 23 2014 at 10:15 in Aud I at Department of Chemistry (1514-213)
Oct 2014 Professor Sijbren Otto, University of Groningen, visits iNANO on October 22 2014 at 15:15 in iNANO aud. (1593-012) and will give a talk on "Systems Chemistry: Molecular Recognition, Catalysis and Self-Replication".
Oct 2014 Dr. Matteo Castronovo, Department of Biology, Temple University, USA, visits iNANO on October 22 2014 and will give a talk on "Nucleic Acid Density is a Crucial Determinant of Enzyme Diffusion, Recognition, and Reactivity at the Nanoscale". Time and place follows
Oct 2014 Professor Chunhai Fan, Shanghai Institute of Applied Physics (SINAP), visits iNANO on October 3 2014 at 10:15 in iNANO aud. (1593-012) and will give a talk on "Creating dynamic organization with DNA nanotechnology".
Oct 2014 PhD defence: Shuai Zhang is defending his PhD thesis, "Amyloid structures on a nanoscale via AFM-based dynamic nanomechanical microscopy" on October 2 2014 at 10:15 in iNANO auditorium (1593-012)
Sep 2014 PhD Defence: Jie Son is defending his PhD thesis, "Exploring Multiscale Materials From Water, DNA to Bacteria" on September 9, 2014 at 14:15 in Lecture Theatre G2, building 1532, room 122, Department of Mathematics.
Aug 2014 Cody Geary and Ebbe S. Andersen publish in Science: "A single-stranded architecture for cotranscriptional folding of RNA nanostructures"
May 2014 CDNA Workshop: The annual CDNA Workshop took place on 21-22 May 2014 with a record high number of participants - 65 CDNA members were gathered at Fuglsøcentret!
May 2014

Kurt Gothelf becomes a new member of the Royal Danish Academy of Sciences and Letters

CDNA meetings

The preliminary dates for CDNA meetings this fall are the following:

Date Time Place
Sep 23 15:15 Aud. VI (Chemistry)
*Oct 20 09:00-11:45 The iNANO Auditorium (1593-012)

* Meeting with the Danish National Research Foundation.

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Revised 2014.10.14

Aarhus University
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DK-8000 Aarhus C

Tel: +45 8715 0000
Fax: +45 8715 0201

CVR no: 31119103

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